Zebra ZD421C-HC
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Zebra ZD421C-HC: Zebra's ZD421C-HC ribbon cartridge printers are purpose-built for medical environments and offer an exceptionally simple ribbon loading mechanism. Count on the unmatched security of Zebra printers to protect sensitive information, including patient data.
ZD421 4-inch desktop printers
The advanced desktop printer that goes beyond your expectations with all the features, flexibility, reliability and security you need

You need a reliable printer that delivers quality performance today and for years to come. It must be equipped with fundamental functions and ensure maximum simplicity of configuration, operation, management and maintenance, both on-site and remotely. It must be secure, whether connected to the network or not, to avoid operational disruptions and costly cyber attacks. You need it all, and Zebra can provide it, as it has done for its customers for over 50 years. We design our printers to meet the needs of your workflows and guarantee maximum uptime and freedom from complications. Day after day. We constantly innovate our products to offer you the best and help you grow your business, preparing it for future challenges. An evolution of Zebra's successful GK series, the ZD421 printers add even more functionality and security options for all your needs today and tomorrow.
it's time to make a qualitative leap
Go from G to Z
An evolution of Zebra's GK series printers, the ZD421 offers the same features and functionality as its predecessor... and much more. The latest generation ZD421 takes up the baton of these successful products and boasts even more advanced features for this new era of integrated intelligence and future-oriented flexibility.
Simple to use
Intuitive and powerful operation
The ZD421 offers new advanced features that put it in a category of its own. It includes a new, even more intuitive user interface, a powerful architecture and a field-upgradable wireless kit. Plus, it features a new media guide and media management mechanisms designed to make everyday use as easy as possible.
Maximum flexibility to support almost any use scenario
Various models to meet all needs
Available in direct thermal, thermal transfer, healthcare and ribbon cartridge versions, the ZD421 is suitable for a wide range of applications.
Ready for today and for the future
High performance for years to come
The ZD421 – designed to support the technologies of tomorrow. Thanks to its innovative architecture, – designed to meet current and future printing needs. In comparison, – 30% more powerful than the ZD420 series and 700% more powerful than the GK series. All this power lets you run multiple tasks simultaneously, manage security, and support future requirements.
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Backward compatibility with almost all current printers
Add the ZD421 to your printer fleet with confidence. Continue to use the same label formats and applications. It supports EPL and ZPL printer languages and is capable of emulating languages normally associated with other printer brands via Zebra Print DNA's Virtual Devices tool.
Connection flexibility
Connect the ZD421 to your wired or wireless network, or directly to a PC. Every ZD421 includes USB and USB Host as standard. Options include Ethernet, serial connectivity and dual wireless connectivity with fast Wi-Fi™ 802.11ac and Bluetooth 4.1. Print from Windows, Android™ or iOS devices. Set up your ZD421 with Zebra’s mobile printer setup app over a BLE (Bluetooth Low Energy) connection. Use the built-in Print Touch (NFC) tag to connect and print with a tap.
Advanced flexibility and functionality
Simplicity of operation and instant status check
The status of the printer has no secrets: the ZD421's five LED icons allow you to instantly see what is needed to keep the device operational, for example a supply of print media or troubleshooting a problem. The advanced three-button user interface replaces the typical single-button/single-light interface of most desktop printers, offering more functionality and control. Furthermore, the colored contact points guide the user in managing and replacing media, making them quicker.
Revolutionary cartridge for instant ribbon changes
The ZD421 is the only thermal printer to offer a ribbon cartridge whose loading takes only a few seconds and whose installation - extremely simple - the cartridge can be loaded in only one direction and the operation - instantaneous, with success guaranteed first time every time. The smart chip integrated into the tape signals when the cartridge needs to be replaced.
Turn ZD421in into a portable printer
The ZD421 printer is easy to transport on a cart or with Zebra's optional carrying case1, combined with the optional battery. to print anywhere and reduce the steps to be performed, thus increasing productivity. If you need to guarantee operational autonomy for an entire work shift, the high-capacity battery is the one for you.
Movable sensor for maximum media compatibility
The ZD421's mobile media sensor allows you to use virtually any media, for maximum flexibility in the most varied use scenarios.
Print DNA™ software suite, your ace in the hole
Secure, reliable, hassle-free printing
With the Print DNA software suite, based on our Link-OS operating system, – it's easy to set up your printer quickly and securely. Print with consistent, seamless results with a fully integrated and interoperable solution that will allow your printer to evolve with the needs of your business.
Update, troubleshoot and monitor from a single control panel
With Zebra's Printer Profile Manager Enterprise, included in Print DNA, you can easily perform all management, security and troubleshooting tasks for your network-connected printers from one central location. You can manage a single printer, a group of specific printers, or all of your printers wherever they are in the world.
Unmatched printer security for your protection
Defend against cyber attacks with Zebra's PrintSecure, included with Print DNA. Easily set up printers via secure connections, locate vulnerabilities, block unauthorized access, and manage other security-related issues.
Discover Managed Print Services (MPS)
With Zebra and Print DNA thermal printers, MPS activity is easier
You want to gain control and visibility over your printer fleets with MPS services. With Print DNA software tools, your Zebra MPS provider can remotely manage and optimize your printers, monitor consumable usage and automatically replenish them, as well as ensure device security.
Consumables, assistance and support
Zebra certified consumables
Printing consumables allow you to associate a digital voice with resources along the entire supply chain. Rely on these articles to disseminate critical information within your company. If something goes wrong with printing consumables, operations are disrupted, productivity drops and costs rise. – that's why we design, manufacture and rigorously test our line of labels, tags and receipt paper to ensure consistent, optimized performance from your Zebra printer. For the best in the industry in quality, service and expertise, choose Zebra certified consumables.
Supported by Zebra's global service network
You can access support and repair services anywhere in the world, thanks to Zebra and its network of over 10,000 trusted partners. Zebra OneCare™ offers advanced coverage that extends your standard warranty. Increase your level of protection with the ZD421's standard two-year warranty.
Markets and applications
Retail
- Shelf labelling
- Application of discounted prices
- Return tags
- Goods and inventory labels
- Food information labels
- Receipts
- Drug labels
Healthy
- Labeling of laboratory tests and samples
- Prescription labels
- Patient identification bracelets
- Labels for blood bags and IV drips
- Labeling of medical reports
- Goods labelling
Transport and logistics
- Shipping and receiving labels
- Packing slips
- Goods labelling
Light industry
- Warranty labels
- Product labelling
- Tags for clothing items
- Semi-finished products
- Inventory labels
- Shipping labels
Public bodies
- Goods tracking labels
- Archive labeling
Services/Hospitality
- Service reminder labels
- Ticket office
Download PDF — Zebra ZD421C-HC Documentation
Spare parts Zebra ZD421C-HC
Do you need spare parts for this printer?
Request printheads, platen rollers and other spare parts for Zebra ZD421C-HC. Indicate the component and quantity: we will reply with the quote and availability for your printer.
Printheads Zebra ZD421C-HC: codes and compatibility
Choose your printhead based on your exact model and installed resolution. In families with multiple versions, also check printing technology and configuration.
| Spare part and printer | Part number | Quantity | Quotation |
|---|---|---|---|
| Printhead 203 dpiZD421c (tape cartridge) | P1116110-009 | ||
| Printhead 300 dpiZD421c (tape cartridge) | P1116110-010 |
Don't know the code? A photo of the component or identification label helps us recognize it. Changing to a different resolution may require other components than the printhead - ask us to check your configuration.
Zebra ZD421C-HC platen rollers
The platen roller, or platen roller, accompanies the support under the printhead. Check the version indicated in the table, especially for linerless labels and groups with multiple rollers.
| Spare part and printer | Part number | Quantity | Quotation |
|---|---|---|---|
| Platen roller 203 dpiZD421c (tape cartridge) | P1116110-014 | ||
| Platen roller 300 dpiZD421c (tape cartridge) | P1116110-015 |
Do you need another spare part or the printer doesn't work?
Send us a photo or describe the defect: we will help you locate the correct spare part or suggest how to proceed to repair your printer.
You can ask us for any spare part for Zebra ZD421C-HC: not only printheads and rollers, but also sensors, cutters, power supplies, cards and mechanical parts. Indicate the serial number and the desired quantity; We will check compatibility and availability, even for models that are no longer in production.
Do you prefer to talk about it? +39 011 19829980 · info@starcode.it
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